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Hypertension

Is a FDC of Metoprolol, Telmisartan & Chlorthalidone Efficacious & Safe in the Treatment of Essential HTN?

A phase-III, open label, multicenter study with 254 adults having stable CAD and uncontrolled hypertension was conducted to evaluate the efficacy and safety of FDC of Metoprolol, Telmisartan and Chlorthalidone in patients showing inadequate response to dual therapy.

FDC1: Metoprolol (25mg)+Telmisartan (40mg)+Chlorthalidone (12.5mg)
FDC2: Metoprolol (50mg)+Telmisartan (40mg)+Chlorthalidone (12.5mg)

Triple FDCs of Metoprolol, Telmisartan and Chlorthalidone Were Effective and Well Tolerated in HTN Patients.

 

FDC: Fixed Dose Combination, HTN: Hypertension, CAD: Chronic Artery Disease, SeDBP: Seated diastolic blood pressure, From the Makers of:
SeSBP: Seated systolic blood pressure, BP:Blood pressure.

References:

Sarkar, G., Gaikwad, V., Sharma, A., Halder, S., et al., 2021. Fixed-dose Combination of Metoprolol, Telmisartan, and Chlorthalidone
for Essential Hypertension in Adults with Stable Coronary Artery Disease: Phase III Study. Advances in Therapy, 39(2), pp.923-942.

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